Table 4.
Therapies Used
| Therapy | No AKI/Stage 1 AKI (n=391) |
Stage 2–3 AKI (n=102) |
p-value |
|---|---|---|---|
| Invasive mechanical ventilation | 283 (72) | 90 (88) | 0.001 |
| Vasoactive infusions | |||
| Any vasoactive infusion | 204 (52) | 78 (76) | <0.001 |
| Norepinephrine | 79 (20) | 44 (43) | <0.001 |
| Epinephrine | 69 (18) | 48 (47) | <0.001 |
| Milrinone | 64 (16) | 23 (23) | 0.145 |
| Dopamine (>5mcg/kg/min) | 62 (16) | 30 (30) | 0.002 |
| Dopamine (≤5mcg/kg/min) | 20 (5) | 4 (4) | 0.798 |
| Dobutamine | 25 (6) | 10 (10) | 0.232 |
| Vasopressin | 11 (3) | 17 (17) | <0.001 |
| Number of vasoactive infusions, median (IQR) |
1 (0, 1) | 2 (1, 3) | <0.001 |
| Synthetic colloid | 15 (4) | 6 (6) | 0.407 |
| Albumin | 83 (21) | 44 (43) | <0.001 |
| Blood products | 136 (35) | 74 (73) | <0.001 |
| Corticosteroids | 155 (40) | 56 (55) | 0.006 |
| Diuretics | 237 (61) | 56 (55) | 0.295 |
| Insulin infusion | 27 (7) | 23 (23) | <0.001 |
| Extracorporeal membrane oxygenation | 15 (4) | 14 (14) | <0.001 |
| Plasma exchange | 1 (0.3) | 3 (3) | 0.029 |
| Catheters | |||
| Foley | 259 (66) | 89 (87) | <0.001 |
| Arterial line | 237 (61) | 80 (78) | 0.001 |
| CVLa (excluding dialysis catheter) | 318 (81) | 97 (95) | 0.001 |
a
CVL: Central venous line