Table 2.
Estimate | SE | Lower 95% CI | Upper 95% CI | p-value | Effect Size | |
---|---|---|---|---|---|---|
Sleep latency | ||||||
CBT-I + Placebo vs. Placebo | -18.62 | 5.25 | -29.14 | -8.10 | <0.001** | -0.67 |
CBT-I + Armodafinil vs. Placebo | -16.16 | 5.27 | -26.73 | -5.59 | 0.003** | -0.58 |
Armodafinil vs. Placebo | 7.98 | 5.68 | -3.45 | 19.41 | 0.17 | 0.29 |
CBT-I + Armodafinil vs. CBT-I + Placebo | 2.46 | 4.67 | -6.70 | 11.61 | 0.60 | 0.09 |
| ||||||
Wake after sleep onset | ||||||
CBT-I + Placebo vs. Placebo | -10.00 | 5.50 | -20.96 | 0.96 | 0.07 | -0.48 |
CBT-I + Armodafinil vs. Placebo | -13.14 | 5.59 | -24.27 | -2.01 | 0.02 | -0.64 |
Armodafinil vs. Placebo | 10.23 | 7.56 | -5.05 | 25.51 | 0.18 | 0.50 |
CBT-I + Armodafinil vs. CBT-I + Placebo | -3.14 | 5.16 | -13.24 | 6.97 | 0.54 | -0.15 |
| ||||||
Total sleep time | ||||||
CBT-I + Placebo vs. Placebo | -28.69 | 19.43 | -67.65 | 10.27 | 0.15 | -0.39 |
CBT-I + Armodafinil vs. Placebo | -16.00 | 20.36 | -56.93 | 24.93 | 0.44 | -0.22 |
Armodafinil vs. Placebo | -51.30 | 21.80 | -95.24 | -7.37 | 0.02 | -0.69 |
CBT-I + Armodafinil vs. CBT-I + Placebo | 12.69 | 17.68 | -21.97 | 47.35 | 0.47 | 0.17 |
P < 0.01,
P < 0.001 A significance level of 0.0125 was used to adjust for multiple comparisons. (Asterisks denote improvements compared to placebo for between group analyses.); All analyses used multiple imputation; P-values for between group analyses are from ANCOVA controlling for values at time of consent; Effect size is Cohen’s D.