Table 4.
Epworth Sleepiness Scale | Estimate | SE | Lower 95% CI | Upper 95% CI | p-value | Effect Size |
---|---|---|---|---|---|---|
Between Group | ||||||
CBT-I + Placebo vs. Placebo | -0.42 | 1.12 | -2.64 | 1.81 | 0.71 | -0.09 |
CBT-I + Armodafinil vs. Placebo | -0.67 | 1.12 | -2.90 | 1.56 | 0.55 | -0.15 |
Armodafinil vs. Placebo | -0.31 | 1.36 | -3.04 | 2.42 | 0.82 | -0.07 |
CBT-I + Armodafinil vs. CBT-I + Placebo | -0.26 | 1.12 | -2.44 | 1.93 | 0.82 | -0.06 |
| ||||||
Post-Pre | SE | Lower 95% CI | Upper 95% CI | p-value | Effect Size | |
| ||||||
Within Group | ||||||
CBT-I + Placebo | -1.91 | 0.73 | -3.47 | -0.35 | 0.02 | -0.51 |
CBT-I + Armodafinil | -1.57 | 0.64 | -2.93 | -0.21 | 0.03 | -0.07 |
Armodafinil | -1.71 | 1.29 | -4.51 | 1.10 | 0.21 | -0.47 |
Placebo | -1.31 | 0.87 | -3.14 | 0.53 | 0.15 | -0.24 |
P < 0.01,
P < 0.001;
A significance level of 0.0125 was used to adjust for multiple comparisons. (Asterisks denote improvements compared to placebo for between group analyses and from pre-intervention for within group analyses and improvements compared to placebo for between group analyses.); All analyses used multiple imputation; P-values for between group analyses are from ANCOVA controlling for values at time of consent; Effect size is Cohen’s D.