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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Sleep Med. 2015 Dec 31;20:18–24. doi: 10.1016/j.sleep.2015.12.010

Table 4.

Comparison of Epworth Sleepiness Scale at post-intervention by study conditions, as well as within group changes from pre-to post-intervention

Epworth Sleepiness Scale Estimate SE Lower 95% CI Upper 95% CI p-value Effect Size
Between Group
CBT-I + Placebo vs. Placebo -0.42 1.12 -2.64 1.81 0.71 -0.09
CBT-I + Armodafinil vs. Placebo -0.67 1.12 -2.90 1.56 0.55 -0.15
Armodafinil vs. Placebo -0.31 1.36 -3.04 2.42 0.82 -0.07
CBT-I + Armodafinil vs. CBT-I + Placebo -0.26 1.12 -2.44 1.93 0.82 -0.06

Post-Pre SE Lower 95% CI Upper 95% CI p-value Effect Size

Within Group
CBT-I + Placebo -1.91 0.73 -3.47 -0.35 0.02 -0.51
CBT-I + Armodafinil -1.57 0.64 -2.93 -0.21 0.03 -0.07
Armodafinil -1.71 1.29 -4.51 1.10 0.21 -0.47
Placebo -1.31 0.87 -3.14 0.53 0.15 -0.24
*

P < 0.01,

**

P < 0.001;

A significance level of 0.0125 was used to adjust for multiple comparisons. (Asterisks denote improvements compared to placebo for between group analyses and from pre-intervention for within group analyses and improvements compared to placebo for between group analyses.); All analyses used multiple imputation; P-values for between group analyses are from ANCOVA controlling for values at time of consent; Effect size is Cohen’s D.