Table 7.

Multivariable association of stratified RSI with intubation outcomes^a

	Success on 1st attempt, Adjusted OR (95% CI) P value	Success ≤2nd attempt, Adjusted OR (95% CI) P value	Complicationsc, Adjusted OR (95% CI) P value	Major complicationsd, Adjusted OR (95% CI) P value
Modified RSIb vs. non-RSI	2.2 (1.5–3.2) P = 0.0012	1.4 (0.9–2.4) P = 0.15	0.7 (0.4–1.2) P = 0.19	0.6 (0.3–1.2) P = 0.16
Modified RSIb vs. intubation with sedative agent only	2.4 (1.6–3.6) P < 0.0001	1.7 (1.0–2.9) P = 0.05	0.6 (0.4–1.1) P = 0.11	0.5 (0.2–1.0) P = 0.07
Modified RSIb vs. intubation without medications	1.9 (1.3–3.0) P = 0.0006	1.1 (0.7–2.0) P = 0.64	0.9 (0.5–1.5) P = 0.55	0.8 (0.3–1.6) P = 0.53

Abbreviation: OR odds ratio, CI confidence interval, RSI rapid sequence intubation

^aAdjusted for age, sex, estimated body weight, principal indication for intubation, device, and the specialties and training level of intubator

^bExcluded cases that used vecuronium, midazolam, diazepam, and haloperidol

^cDefined as cardiac arrest, hypotension, hypoxemia, regurgitation, esophageal intubation with delayed recognition, main stem bronchial intubation, dental or lip trauma, airway trauma, or allergic reaction

^dDefined as cardiac arrest, hypotension, hypoxemia, regurgitation, or esophageal intubation with delayed recognition