Table 2.
Patients' characteristics for the whole cohort.
| Total number of patients (n = 376) |
|
|---|---|
| Trials | |
| Ludman [27] | 40 (11%) |
| Crimi [28] | 76 (20%) |
| Garcia-Dorado [30] | 177 (47%) |
| White [29] | 83 (22%) |
| Randomization | |
| Intervention | 191 (51%) |
| Placebo | 185 (49%) |
| Age | 59 ± 12 |
| Sex — male | 193 (51%) |
| Risk factors | |
| Smoking | 221 (59%) |
| Hypertension | 166 (44%) |
| Dyslipidemia | 117 (31%) |
| Diabetes Mellitus | 55 (15%) |
| Family history of CAD | 72 (19%) |
| Pre-infarct angina | 108 (29%) |
| Onset to balloon time/min | 215 ± 97 |
| Artery involved | |
| LAD | 211 (56%) |
| RCA | 71 (19%) |
| Cx | 94 (25%) |
| TIMI flow pre-PPCI | |
| 0 | 365 (97%) |
| 1 | 11 (3%) |
| Rentrop collateral flow | |
| 0 | 287 (76%) |
| 1 | 61 (16%) |
| 2 | 28 (7%) |
| TIMI flow post-PPCI | |
| 1 | 1 (1%) |
| 2 | 43 (11%) |
| 3 | 330 (88%) |
| CMR details | |
| LVEDV | 154 ± 36 |
| LVESV | 78 ± 31 |
| LVEF | 50 ± 11 |
| MI size/%LV | 22 ± 11 |
| AAR/%LV | 33 ± 12 |
| MI size/%AAR | 64 ± 21 |
| MVO/% | 111 (53%) |
CAD: coronary artery disease; LAD: left anterior descending artery; RCA: right coronary artery; Cx: circumflex artery; TIMI: Thrombolysis In Myocardial Infarction; PPCI: primary percutaneous coronary intervention; LVEDV: left ventricular end diastolic volume; LVESV: left ventricular end systolic volume; LVEF: left ventricular ejection fraction; AAR: area at risk; LV: left ventricle; MVO: microvascular obstruction.