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. Author manuscript; available in PMC: 2017 Jan 26.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Mar 7;49(7):3134–3142. doi: 10.1167/iovs.07-1649

Figure 7.

Figure 7

Single channel currents of wild-type and mutant mucolipin-1 proteins. Representative single channel for wild-type (A) and D1740G mutant mucolipin-1 (B). Tracings were obtained by reconstituting the in vitro-translated protein, in a lipid bilayer exposed to a KCl chemical gradient. Holding potentials are indicated above the tracings. (C) Current-to-voltage relationships for wild-type and D1740G mucolipin-1. Values are the average single-channel currents of seven experiments for the wild-type, and six for the mutant mucolipin-1.