. Author manuscript; available in PMC: 2017 Jan 26.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Jul 10;28(10):1745–1752. doi: 10.1161/ATVBAHA.108.169680

Table.

Plasma Lipid Levels in Ldlr^−/− Apobec1^−/− Mice With Wild-Type ApoB100 or ApoB100-β Mutation

	Apob Genotype	Normal Chow Diet		High-Fat Western Diet
	Apob Genotype	TC (mg/dl)	TG (mg/dl)	TC (mg/dl)	TG (mg/dl)	FC (mg/dl)	PL (mg/dl)
F	100/100	380±31(15)	78±6 (15)	1005±35 (24)	134±14 (20)	253±37 (15)	627±23 (10)
	100/100-β	196±7 (10)	36±3 (10)	476±82 (6)	124±56 (6)	143±36 (10)	342±21 (10)
	100-β/100-β	93±6 (15)	23±3 (15)	292±24 (19)	60±5 (15)	84±14 (8)	236±8 (8)
M	100/100	478±23 (7)	99±7 (7)	1161±26 (11)	599±22 (11)	n.d.	n.d.
	100/100-β	256±10 (8)	60±9 (8)	n.d.	n.d.	n.d.	n.d.
	100-β/100-β	126±7 (8)	39±4 (8)	329±20 (7)	149±29 (7)	n.d.	n.d.

Data are mean±SE in mg/dl. Plasma samples were collected from mice after a 4-hr fast. The numbers in parentheses are the No. of animals. F indicates females; M, males; TC, total cholesterol; TG, triglycerides; FC, free cholesterol; PL, phospholipids; n.d., not determined. Effects of Apob genotypes are highly significant in all categories (P<0.0001).