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. 2017 Jan 21;10:463–476. doi: 10.2147/OTT.S119362

Table 2.

US FDA approved nanomedicines used for cancer treatments

Drug Class Platform Drug carried ratio Diameter (mm) Dose (mg2/m) References
Doxorubicin Liposome Doxil® 10,000–15,000 100 25–80 Gabizon et al16 and Hamilton et al138
Vincristine Liposome Marqibo ~10,000 100 2.0–2.25 Bedikian et al139 and Silverman and Deitcher140
Daunorubicin Liposome Daunoxome ~10,000 50 10–190 Gill et al141 and Bellott et al142
Mertansine Antibody–drug conjugates Trastuzumab emtansine ≤8 ~10 10–160 Lu et al143
Monomethyl auristan E Antibody–drug conjugates Brentuximab vedotin ≤8 ~10 90–110 Younes et al144 and Bradley et al145
Paclitaxel Protein carrier Abraxane® >10,000 130 150–300 Ando et al146

Abbreviation: FDA, Food and Drug Administration.