Table 2.
Drug | Class | Platform | Drug carried ratio | Diameter (mm) | Dose (mg2/m) | References |
---|---|---|---|---|---|---|
Doxorubicin | Liposome | Doxil® | 10,000–15,000 | 100 | 25–80 | Gabizon et al16 and Hamilton et al138 |
Vincristine | Liposome | Marqibo | ~10,000 | 100 | 2.0–2.25 | Bedikian et al139 and Silverman and Deitcher140 |
Daunorubicin | Liposome | Daunoxome | ~10,000 | 50 | 10–190 | Gill et al141 and Bellott et al142 |
Mertansine | Antibody–drug conjugates | Trastuzumab emtansine | ≤8 | ~10 | 10–160 | Lu et al143 |
Monomethyl auristan E | Antibody–drug conjugates | Brentuximab vedotin | ≤8 | ~10 | 90–110 | Younes et al144 and Bradley et al145 |
Paclitaxel | Protein carrier | Abraxane® | >10,000 | 130 | 150–300 | Ando et al146 |
Abbreviation: FDA, Food and Drug Administration.