Table 3.
Physicochemical properties of selected natural inhibitors
| Natural inhibitor | Molecular weight (Da) | Polar surface area (Å2) | Molecular surface area (Å2) | Partition coefficient (log P) |
|---|---|---|---|---|
| Brassinin | 236.35 | 27.82 | 310.98 | 3.28 |
| Annulin A | 360.35 | 110.13 | 501.95 | 3.20 |
| Annulin B | 386.39 | 106.97 | 547.34 | 4.13 |
| Adociaquinone A | 520.77 | 110.52 | 423.438 | 1.10 |
| Adociaquinone B | 423.43 | 110.52 | 520.92 | 1.10 |
| Exiguamine A | 492.50 | 146.03 | 647.56 | −1.85 |
| Tryptamine | 160.21 | 41.81 | 252.62 | 1.49 |
| Curcumin | 368.37 | 93.06 | 509.73 | 4.12 |
| Epigallocatechin gallate | 458.37 | 197.37 | 556.67 | 3.08 |
| Tryptanthrin | 248.23 | 49.74 | 299.16 | 2.40 |
| 3,3′-Diindolylmethane | 246.30 | 31.58 | 352.74 | 4.26 |
| p-Coumaric acid | 164.15 | 57.53 | 216.51 | 1.83 |
| Thielavin | 580.62 | 148.82 | 869.53 | 9.30 |
Note: Physicochemical properties of selected natural inhibitors retrieved from Watkins et al.147