Table 4.
Physicochemical properties of selected synthetic inhibitors
| Synthetic inhibitors | Molecular weight (Da) | Polar surface area (Å2) | Molecular surface area (Å2) | Partition coefficient (log P) |
|---|---|---|---|---|
| Norharman (9H-pyrido [3,4-b]indole) | 168.19 | 28.68 | 230.63 | 1.87 |
| 4-Phenylimidazole | 144.17 | 28.68 | 211.56 | 1.89 |
| Salicylic acid | 138.12 | 57.53 | 183.54 | 1.98 |
| Ascorbic acid | 176.12 | 107.22 | 208.27 | −1.91 |
| Nitric oxide | 30.00 | 34.14 | 48.22 | −0.35 |
| 1-Methyl tryptophan | 218.25 | 68.11 | 322.23 | 1.32 |
| 2-Mercapto-benzothiazole | 167.25 | 12.89 | 191.43 | 2.89 |
| 2-Mercapto-4-phenylthiazole | 193.28 | 12.89 | 236.29 | 3.44 |
| Phenylthiazole | 161.22 | 12.89 | 215.12 | 2.66 |
| Imidodicarbonimidic diamide | 101.11 | 111.77 | 130.40 | −1.46 |
| 4-Amino-1,2,5-oxadiazole-3-carboximidamide | 127.10 | 114.81 | 147.82 | −1.37 |
| Phenformin | 205.25 | 102.78 | 302.68 | 0.34 |
| Cinnabarinic acid | 300.22 | 139.28 | 311.10 | 0.44 |