Table 2. Characteristics of optic neuritis attacks and outcome—functional and anatomic.

Pt.No.	No. of ON attacks	Disc edema during ON	Visual acuity at worst ON episode		Final visual acuity		Final visual field mean deviation (dB)		Final average RNFL (μm)		ICD-10/WHO Visual Disability scale
			RE	LE	RE	LE	RE	LE	RE	LE
Patients with MOG-IgG positive optic neuritis
1	Total—3 Bilateral—2 Left—1	+	3.00	2.00	0.0	0.0	-1.15	-0.84	60	59	Normal
2	Total—1 Bilateral—1	+	2.00	0.70	0.0	0.16	-2.99	-0.94	96	102	Mild
3	Total—2 Bilateral—2	+	2.00	2.00	0.08	0.1	-2.58	-2.11	78	64	Normal
4	Total—1 Right—1	+	0.04	0.04	0.0	0.0	-2.64	-3.62	70	82	Mild
5	Total—2 Left—2	+	0.16	0.24	0.0	0.0	-0.77	-3.1	91	60	Normal
6	Total—1 Right—1	+	0.86	0.16	0.0	0.0	-1.44	-0.32	70	72	Normal
Patients with AQP4-IgG positive optic neuritis
1	Total—2 Left—2	-	0.0	2.00	0.06	0.16	-0.38	-11.08	79	49	Mild
2	Total—3 Right—3	-	3.00	0.7 (amblyopia)	0.06	0.54	-9.36	-3.52	54	86	Moderate
3	Total—5 Right—2 Left—3	-	0.04	0.03	0.0	0.0	-3.31	-1.42	50	52	Mild
4	Total—4 Right—1 Left—3	-	0.16	3.00	0.0	3.00	+1.11	UA	91	32	Mild
5	Total—4 Right—4	-	UA	UA	0.0	0.0	-2.80	-1.91	56	77	Normal
6	Total—5 Right—3 Left—2	-	0.16	1.38	0.16	0.1	-17.99	-11.12	45	46	Mild
7	Total—4 Right—3 Left—1	-	2.00	1.255	0.0	0.0	-1.26	-2.02	72	66	Mild
8	Total—1 Right—1	-	UA	UA	0.06	0.1	-3.90	-7.30	54	78	Mild
9	Total—4 Bilateral—1 Right—1 Left—2	+	0.04	3.00	0.0	0.06	-9.62	-7.56	60	64	Mild
10	Total—3 Right-1 Left—2	-	0.0	1.86	0.0	1.2	-0.02	Spot size V, average sensit. 300 DB	77	53	Mild

UA = unavailable, ON = optic neuritis

Disc edema occurred in all MOG-IgG associated ON events and in all ON events of patient no. 9 with AQP-IgG associated NMOSD.