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. 2017 Jan 26;11(1):e0005238. doi: 10.1371/journal.pntd.0005238

Fig 7. Salient histopathological features in the lower limb in mice injected with CHIKV (Group 1).

Fig 7

1) Whole mount section of the lower limb showing bluish patches of reactive calcification along the margins of the thigh muscle (x 2. H & E stain). 2) Reveals features of myositis with inflammatory infiltrate in Panel (*I). 3) Muscle necrosis with dense inflammatory infiltrate spreading in the endomysium (*N). 4) Mineralization of the necrosed tissue visible as dark blue flakes (*C). 5) Regeneration of the muscle fibres with the bluish pink colour (*R). 6) Hyperplasia of the bone marrow with prominent megakaryocytes. (Scale bar -200μM, H & E stain).