Table 3. Compilation of salient features observed in histopathology among various experimental groups in the study and the overall inflammation score.
EXPERIMENTAL GROUPS | SALIENT FEATURES NOTED IN HISTOPATHOLOGY IN EACH EXPERIMENTAL GROUP | ||||||
---|---|---|---|---|---|---|---|
MYOSITIS | MUSCLE NECROSIS | MINERALISATION OF NECROSED MUSCLE | REGENERATION OF MUSCLES | VASCULITIS | HYPERPLASIA OF MARROW | OVERALL INFLAMMATION SCORE | |
GROUP 1 Virus control |
PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | 3+ |
GROUP 2 Mock infected |
ABSENT | ABSENT | ABSENT | ABSENT | ABSENT | ABSENT | 1 + |
GROUP 3 Peptide A control |
PRESENT | PRESENT | ABSENT | ABSENT | PRESENT | PRESENT | 3+ |
GROUP 4 Peptide B control |
PRESENT | PRESENT | ABSENT | ABSENT | PRESENT | PRESENT | 3+ |
GROUP 5 Non specific peptide control |
ABSENT | ABSENT | ABSENT | ABSENT | ABSENT | PRESENT | 1+ |
GROUP 6 No peptide control |
ABSENT | ABSENT | ABSENT | ABSENT | ABSENT | ABSENT | 1+ |
GROUP 7 CHIKV + Peptide A |
PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | 4+ |
GROUP 8 CHIKV+ Peptide B |
PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | PRESENT | 4+ |
GROUP 9 CHIKV + Non specific peptide |
PRESENT | PRESENT | PRESENT | ABSENT | PRESENT | PRESENT | 3+ |