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. 2017 Jan 26;12(1):e0170897. doi: 10.1371/journal.pone.0170897

Table 2. Comparison of KRAS mutation analysis in FFPE EUS-FNA by dPCR and surgically resected tissue by Sanger sequencinga.

dPCR in EUS-FNA FFPE sections
KRAS mutation status WT G12V or G12Db (1 mutation) G12V and G12D (2 mutations)
Sanger sequencing in surgically resected tissues WT 1 0 0
G12V or G12D (1 mutation) 0 22 4
G12V and G12D (2 mutations) 0 0 1

aCytologically benign samples are excluded from this table as none of these patients underwent surgical resection

bKRAS mutation subtypes matched between dPCR and Sanger sequencing for all patients in this category

Abbreviations: dPCR; digital PCR, WT; wild-type