Table 3.

Pathways significantly changing with progression of puberty. The 13 significant pathways associated with pubertal maturation of the growth plate are shown

Pathway	Genes found	Total genes pathway	%	P
1. Proteasome	9	23	39	‡
2. Cholera infection	10	30	33	‡
3. Oxidative phosphorylation	20	89	22	‡
4. N Glycan biosynthesis	9	27	33	†
5. ATP synthesis	9	28	32	†
6. Adherens junction	14	60	23	†
7. Aminosugars metabolism	6	17	35	†
8. Regulation of autophagy	6	17	35	†
9. Ribosome	9	35	26	†
10. ECM receptor interaction	14	67	21	†
11. Cell cycle	15	84	18	*
12. Cell communication	13	74	18	*
13. Ubiquitin-mediated proteolysis	7	32	22	*

^*P < 0.05,

^†P < 0.01,

^‡P < 0.001.