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. 2017 Jan 26;5(2):e13084. doi: 10.14814/phy2.13084

Figure 3.

Figure 3

Albumin excretion rate measurements by ELISA in (A) control + vehicle (n = 6), (B) control + Ac‐SDKP (n = 6), (C) SLE + vehicle (n = 10), and (D) SLE + Ac‐SDKP (n = 10). The albumin excretion rate was monitored weekly from 25 to 38 weeks of age. Vehicle or Ac‐SDKP (800 μg/kg per day) were infused via osmotic minipump from the age of 24 weeks. The recording of each individual mouse albumin excretion is represented in different colors, and the mouse ID number is shown in the figure inset. Some animals developed flares and remissions, whereas others did not show any indication of albuminuria. The time frame of albuminuria development in the SLE + veh group varied from 27 to 37 weeks of age. Ac‐SDKP tended to delay the development of massive albuminuria and death in SLE‐Hyp. Ac‐SDKP, N‐acetyl‐seryl‐aspartyl‐lysyl‐proline; SLE, systemic lupus erythematosus.