Skip to main content
. Author manuscript; available in PMC: 2017 Mar 28.
Published in final edited form as: Gene Ther. 2016 Sep 28;24(1):12–20. doi: 10.1038/gt.2016.69

Figure 6.

Figure 6

Vector-genome junctions of transduced HEK293 clones. Summary of results obtained from sequencing of Zeocin selected clones transduced with a normal integrating vector (CS-CZW), an integrase catalytic core mutant NILV (IN/D116N), a U3 LTR integrase attachment sited deleted NILV (LTR/U3att) and a double mutant (LTR/U3att-IN/D116N).Red highlighted base-pairs indicate flanking 5-bp repeat of genomic DNA by integrase-mediated strand-transfer; underlined TG/CA dinucleotides represent end-processing by a functional integrase protein; inverted black triangles represent LTR truncations; red highlighted triangle represents deletions of genomic DNA; black squares indicate insertions at the vector-genome junction.