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. Author manuscript; available in PMC: 2018 Jan 25.
Published in final edited form as: Cell Syst. 2016 Nov 17;4(1):46–59.e4. doi: 10.1016/j.cels.2016.10.014

Figure 1.

Figure 1

Identification of the Osteoblast Functional Module (OFM). A). Overview of the approach used to predict genes responsible for BMD GWAS associations. B). Enrichment of genes located in BMD GWAS regions in network modules 6 and 9. C). Eigengenes for modules 6 and 9 cluster. D). Module 6 and 9 eigengenes are highly correlated. E). Gene ontology fold enrichments and F) significance are correlated for GO terms shared between modules 6 and 9. G). The OFM is a cohesive, highly interconnected functional module. OFM genes with a topological overlap measure (TOM) of 0.05 are connected. A darker red color indicates increased number of connections with other OFM genes.