Fig. 4. BLSA network changes are preserved in the Emory proteome.
(A) In the BLSA proteomic network, 13 of the 16 modules were highly preserved in the Emory proteomic network, with Zsummary scores above 2 (p<0.05). Larger modules were some of the most preserved (above red line, p<0.01). (B) Emory protein modules and top hub proteins that increased in AD selectively or across all neurodegenerative diseases. (C) Emory protein modules and top hub proteins that decreased in AD selectively or across all neurodegenerative diseases. Significance was measured using one-way nonparametric ANOVA, Kruskal-Wallis p-values.