. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Dec 1;37(2):191–204. doi: 10.1161/ATVBAHA.116.306256

Table 2.

Sudden death registry data of coronary plaque characteristics relative to diabetic status

	Type 1 DM (n=16)	Type 2 DM (n=50)	Non-DM (n=66)	P Value (Type 1 DM vs. non-DM)	P Value (Type 2 DM vs. non-DM)
Necrotic core area (%) ^*	12.0±5.7	11.6±8.4	9.4±9.3	0.05	0.004
Macrophage plaque area (mm²) ^*	0.15±0.02	0.13±0.03	0.10±0.02^†	0.03	0.03
Calcified matrix area (%) ^*	7.8±9.1	12.1±11.2	11.4±13.5	0.9	0.05
Fibroatheroma (n)	7.1±5.0	8.8±4.3	6.9±4.7	0.9	0.02
Thin-cap fibroatheroma (n)	1.0±1.3	0.8±0.8	0.7±0.8	0.5	0.8
Healed plaque rupture (n)	2.6±2.1	2.6±1.8	1.9±1.8	0.2	0.04
Total plaque burden (%)	275±129	358±114	232±128	0.04	0.0001
Distal plaque burden (%)	310±114	630±263	331±199	0.8	0.0001

Values are expressed as mean ± SD or % normalized to plaque area.

p values calculated using log-normalized data.

^†

p=0.006 vs. type 1 and 2 diabetes combined. DM=diabetes mellitus. Reproduced with permission from Burke AP et al., Arterioscler Thromb Vasc Biol. 2004;24:1266-1271