Table 1.
Variables | Totaln = 166 | Hepcidin‐25, <35 ng/mLn = 83 | Hepcidin‐25, ≥35 ng/mLn = 83 | P value |
---|---|---|---|---|
Age at transplant (years) | ||||
Median (range) | 49.5 (17–66) | 47 (17–65) | 51 (19–66) | 0.22 |
Sex | ||||
Male | 92 | 48 | 44 | 0.64 |
Female | 74 | 35 | 39 | |
Disease | ||||
Myeloid malignancies | 103 | 49 | 54 | 0.52 |
Lymphoid malignancies | 63 | 34 | 29 | |
Risk of disease | ||||
Standard | 100 | 53 | 47 | 0.43 |
High | 66 | 30 | 36 | |
Source of stem cells | ||||
HLA‐matched related | 31 | 18 | 13 | 0.66 |
HLA‐mismatched related | 13 | 5 | 8 | |
Unrelated BM or PBa | 75 | 38 | 37 | |
Unrelated CB | 47 | 22 | 25 | |
ABO blood‐type matching | ||||
Matched | 67 | 32 | 35 | 0.75 |
Mismatched | 99 | 51 | 48 | |
Conditioning regimen | ||||
Myeloablative intensity | 79 | 45 | 34 | 0.12 |
Reduced intensity | 87 | 38 | 49 | |
GVHD prophylaxis | ||||
Tacrolimus‐based | 143 | 68 | 75 | 0.18 |
Cyclosporine‐based | 23 | 15 | 8 |
Among the stem cell sources from unrelated donors, all but 1 were BM.
Patient and transplant characteristics between two groups were compared using the Mann–Whitney U‐test or Fisher's exact test, as appropriate. HLA, human leukocyte antigen; BM, bone marrow; PB, peripheral blood; CB, cord blood; GVHD, graft‐versus‐host disease; tacrolimus‐based, tacrolimus with or without other agents; cyclosporine‐based, cyclosporine with or without other agents.