Table 1. Dissociation Constants for GH99 endo-Mannanase Inhibitors.

	KD values (μM)
compd	BtGH99	BxGH99	method
1 (GlcDMJ)	24	NDa	ITC12
2 (GlcIFG)	0.63	NDa	ITC12
3 (ManIFG)	0.14	0.27	ITC6
5 (ManddMan)	53 ± 5	221 ± 11	NMR
7 (ManGlucal)	15 ± 1.9	111 ± 11	NMR
8 (GlcChex)	no binding	no binding	NMR/ITC
9 (ManNOE)	0.03 ± 0.01	0.013 ± 0.002	ITC

^aND, not determined.