Table 2. Univariate predictors of CI-AKI derived by logistic regression analysis.
Variable | Patients without CIN (n = 559)Mean/median (±SD/Q1–Q3) | Patients with CIN (n = 58)Mean/median (±SD/Q1–Q3) | OR (95%-CI) | p-value |
---|---|---|---|---|
Age, y | 74 (68–80) | 76 (71–80) | 1.03 (0.99–1.06) | 0.13 |
BMI, kg/m2 | 27.25 ± 4.25 | 26.71 ± 3.44 | 0.97 (0.90–1.03) | 0.31 |
MAPday-1, mmHg | 97.48 ± 13.22 | 96.26 ± 13.75 | 0.99 (0.97–1.01) | 0.46 |
Contrast volume, ml | 110.12 ± 51.74 | 118.90 ± 54.83 | 1.00 (0.99–1.01) | 0.18 |
eGFRday-1, ml·min−1·1.73m−2 | 48.68 ± 12.66 | 53.12 ±10.05 | 1.03 (1.01–1.06) | 0.006 |
Se-Creatinineday-1, mg/dl | 1.36 ± 0.41 | 1.19 ± 0.27 | 0.2 (0.07–0.50) | 0.001 |
Cystatin Cday-1, mg/L, | 1.28 ± 0.45 | 1.21 ± 0.38 | 0.67 (0.32–1.28) | 0.26 |
Urine osmolalityday-1, mOsm/kgH2O | 470 (370–610) | 460 (370–580) | 0.99 (0.99–1.00) | 0.46 |
Urinary proteinday-1, mg/gCreatinine | 100 (69–190) | 110 (77–170) | 1.00 (0.99–1.00) | 0.89 |
uNGAL (ng/ml)day-1 | 19 (9–49) | 18 (9.2–48) | 0.96 (0.58–1.58) | 0.89 |
uNGAL (μg/gCrea)day-1 | 25 (12–57) | 24 (13–76) | 1.11 (0.67–1.83) | 0.68 |
uNGAL (ng/ml)day0 | 11 (6–27) | 13 (5–40) | 1.04 (0.64–1.7) | 0.76 |
uNGAL (μg/gCrea)day0 | 20 (10–44) | 20 (11–57) | 1.07 (0.65–1.8) | 0.54 |
Sex (n, %) | ||||
Female | 256 (45.8) | 31 (53.4) | ||
Male | 303 (54.2) | 27 (46.6) | 0.74 (0.43–1.26) | 0.27 |
Diabetes (n, %) | ||||
No | 330 (59) | 41 (70.7) | ||
Yes | 229 (41) | 17 (29.3) | 0.60 (0.32–1.06) | 0.09 |
Heart disease (n, %) | ||||
No | 108 (19.3) | 8 (13.8) | ||
Yes | 451 (80.7) | 50 (86.2) | 1.5 (0.73–3.50) | 0.31 |
Hypertension (n, %) | ||||
No | 80 (14.3) | 7 (12.1) | ||
Yes | 479 (85.7) | 51 (87.9) | 1.22 (0.57–3.00) | 0.64 |
Diuretics (n, %) | ||||
No | 207 (37) | 20 (34.5) | ||
Yes | 352 (63) | 38 (65.5) | 1.12 (0.64–2.00) | 0.7 |
RAAS-Blocker (n, %) | ||||
No | 131 (23.4) | 13 (22.4) | ||
Yes | 428 (76.6) | 45 (77.6) | 1.06 (0.57–2.10) | 0.86 |
Statins (n, %) | ||||
No | 99 (37.4) | 7 (25.0) | ||
Yes | 166 (62.6) | 21 (75.0) | 1.79 (0.77–4.7) | 0.2 |
Angiography (n, %) | ||||
Coronary | 385 (62.4) | 42 (72.4) | ||
Peripheral arteries | 213 (34.5 | 14 (24.1) | 0.57 (0.3–1.1) | 0.08 |
other | 19 (3.08) | 2 (3.45) | 0.96 (0.15–3.50) | 0.96 |
OR = odds ratio, CI = confidence interval.