Table 3. Association of absolute baseline uNGAL and uNGAL normalized to creatinine with clinical variables.
Variable | Baseline uNGAL (ng/ml)Median (95%-CI) | p-value | Baseline uNGAL (μg/g Creatinine)Median (95%-CI) | p-value |
---|---|---|---|---|
Sex | ||||
Female | 31 (25–36) | <0.0001 | 40 (33–46) | <0.0001 |
Male | 16 (13–18) | 19 (18–21) | ||
Age, years | ||||
≤74 | 17 (15–22) | 0.009 | 21 (18–24) | <0.0001 |
>74 | 22 (19–27) | 30 (25–35) | ||
BMI, kg/m2 | ||||
≤27 | 20 (17–24) | 0.94 | 25 (22–29) | 0.66 |
>27 | 19 (16–24) | 24 (20–29) | ||
Diabetes | ||||
yes | 24 (18–31) | 0.002 | 30 (26–37) | 0.0002 |
No | 18 (15–22) | 22 (20–25) | ||
Hypertension | ||||
yes | 19 (17–23) | 0.86 | 25 (22–28) | 0.38 |
No | 23 (14–29) | 22 (18–28) | ||
Heart disease | ||||
yes | 18 (16–22) | 0.005 | 24 (22–26) | 0.03 |
No | 29 (20–36) | 30 (23–42) | ||
Se-Creatinine (mg/dl), day-1 | ||||
≤1.2 | 19 (16–24) | 0.57 | 24 (21–28) | 0.38 |
>1.2 | 20 (17–24) | 26 (22–29) | ||
eGFR (ml·min−1·1.73 m−2), day-1: | 21 (17–26) | |||
>60 | 18 (14–24) | 0.0002 | 21 (18–24) | <0.0001 |
59–45 | 17 (13–22) | 30 (27–39) | ||
44–30 | 22 (18–27) | 49 (34–72) | ||
29–15 | 44 (28–54) | 20 (20–20) | ||
<15 | 7 (7–7) | |||
Cystatin C (mg/L), day-1 | ||||
≤1.2 | 18 (15–22) | 0.001 | 21 (18–23) | <0.0001 |
>1.2 | 22 (18–27) | 33 (27–37) | ||
Osmolalityurine (mOsm/kgH2O), day-1 | ||||
≤470 | 14 (12–17) | <0.0001 | 30 (26–36) | <0.0001 |
>470 | 26 (22–30) | 21 (19–23) | ||
Urinary protein (mg/gCreatinine) day-1 | ||||
≤100 | 16 (13–18) | <0.0001 | 18 (16–20) | <0.0001 |
>100 | 27 (22–31) | 37 (33–44) | ||
Hospital stay (days) | ||||
≤2 | 20 (17–24) | 0.54 | 26 (24–29) | 0.42 |
>2 | 18 (16–24) | 22 (20–28) |
P-values were derived from Kruskal-Wallis test. Continuous variables were grouped into above and below the median with 95% confidence intervals in parenthesis.