Table 2.
Characteristics of patients with secondary primary malignancies
| SPM | Gender | Age Dx of SPM | Time from Dx to SPM (years) | Time from last ASCT to start of Len‐dex (months) | Duration from start Len to SPM Dx (months) | Duration from SPM Dx to death (months) | No. of prior ASCT | Radiation prior SPM (site) | Smoking history | Oral cyclo exposure prior SPM (months) |
|---|---|---|---|---|---|---|---|---|---|---|
| MDS/RAEB‐2 | Male | 72 | 5 | N/A | 19 | 10 | 0 | Yes (Spine) | N/A | 13.9 |
| MDS/SCC | Female | 79 | 10 | N/A | 34 | 1 | 0 | Yes (Spine) | N/A | 20.2 |
| MDS/PCL | Male | 56 | 4 | 12 | 23 | 7 | 1 | No | Yes | 0 |
| MDS | Female | 73 | 8 | 57 | 19 | 13 | 1 | Yes (Spine) | No | 20.7 |
| MDS | Male | 63 | 2 | 23 | 2 | 5 | 2 | No | Yes | 0 |
| AML | Female | 66 | 10 | 41 | 57 | 7 | 2 | Yes (Spine) | Yes | 0 |
| Adenocarcinoma of rectum | Male | 65 | 6 | 29 | 31 | 4 | 1 | Yes (colon) | No | 0 |
| Cholangiocarcinoma | Female | 66 | 5 | 43 | 15 | 2 | 1 | Yes (lumbar spine) | Yes | 2.4 |
| SCC of Tonsil | Female | 70 | 7 | 43 | 38 | 4 | 1 | N/A | Yes | 12.2 |
| Urethral cancer | Female | 72 | 15 | 58 | 70 | 11 (Alive) | 2 | Yes (extra‐medullary disease) | N/A | 4.3 |
| SCC of head and neck | Male | 75 | 8 | N/A | 79 | 1 (Alive) | 0 | No | No | 13.2 |
SPM, secondary primary malignancies; N/A, not available; Dx, diagnosis; PCL, plasma cell leukemia; MDS, myelodysplastic syndrome; SCC, squamous cell carcinoma; ASCT, autologous stem cell transplant; RAEB, refractory anemia with excess of blasts.