Table 2. Cancer datasets used in this study.

Dataset	Cancer	Mutations	Genomes
Alexandrov	Breast	655,823	119
Alexandrov	CLL	51,377	28
Alexandrov	Liver	867,080	88
Alexandrov	Lung_adeno	1,520,078	24
Alexandrov	Lymphoma_B-cell	126,581	24
Alexandrov	Medulloblastoma	123,642	100
Alexandrov	Pancreas	110,944	15
Alexandrov	Pilocytic_astrocytoma	10,436	101
Alexandrov	Stad	2,796,863	100
Alexandrov	Pancancer	6,259,996	607
TCGA	BLCA	385,128	21
TCGA	BRCA	620,238	96
TCGA	CRC	4,680,653	42
TCGA	GBM	180,896	27
TCGA	HNSC	295,709	27
TCGA	KICH	24,508	15
TCGA	KIRC	131,828	29
TCGA	LGG	35,474	18
TCGA	LUAD	1,237,722	46
TCGA	LUSC	1,626,973	45
TCGA	PRAD	21,113	20
TCGA	SKCM	3,538,750	38
TCGA	THCA	37,882	34
TCGA	UCEC	2,268,210	47
TCGA	Pancancer	14,841,279	505
Both	Superpancancer	20,837,263	1112