Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 27;7:41517. doi: 10.1038/srep41517

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Upf1-bound transcripts whose log2-fold expression was decreased by 1.5 fold or was completely absent from SE samples and whose log2-fold expression was increased 1.5 fold or was completely absent from control samples were used to investigate over- and under-represented GO terms. Numbers of genes in each group are displayed in inset Venn diagram. (a) Biosynthetic and mRNA processes were over-represented in those genes only expressed or decreased in control SN sample. (b) Terms relating to biosynthetic, biological (conversely to control), and GPCR signalling were over-represented in the group of genes that were increased or exclusively bound after SE in SN compartment. (c) RNA processes, GPCR and glutamate signalling were over-represented in the genes that were exclusive to or decreased in control cytoplasm. (d) GO terms related to biological processes, biosynthetic processes, cell signalling, development (Dev.) and G protein coupled receptor (GPCR) signalling were over-represented by the genes that were exclusive to or increased after SE in cytoplasm. There was an under-representation of genes associated with responses to a stimulus in all groups and genes related with immune response were also under-represented in both the SN and cytoplasm fractions for genes exclusive to or decreased in controls.