Table 3. Comparison of risk allele frequencies, odds ratios and population-attributable risk percentages between Chinese and Europeans.
| SNP | Risk allele | Gene | Chinese/European controls (1121 vs. 15991) |
OR (Chinese/European) | PARP (Chinese/European) | |
|---|---|---|---|---|---|---|
| RAF% | Allele P | |||||
| rs6740462 | A | SPRED2 | 77.0/73.5 | 9.44 × 10−3 | 1.23/1.20 | 15.05%/12.82% |
| rs3768792 | G | IKZF2 | 19.2/12.9 | 2.18 × 10−9 | 1.09/1.26 | 1.70%/3.25% |
| rs564799 | C | IL12A | 84.7/59.3 | 3.27 × 10−64 | 1.37/1.15 | 23.86%/8.17% |
| rs7726414 | T | TCF7 | 5.7/4.4 | 4.54 × 10−2 | 1.53/1.46 | 2.93%/1.98% |
| rs3794060 | C | DHCR7, NADSYN1 | 49.5/25.6 | 4.20 × 10−68 | 1.19/1.13 | 8.60%/3.22% |
| rs10774625 | A | SH2B3 | 99.4/50.1 | 2.08 × 10−225 | 1.56/1.17 | 35.76%/7.85% |
| rs4902562 | A | RAD51B | 58.8/41.7 | 2.83 × 10−29 | 1.09/1.13 | 5.03%/5.14% |
| rs9652601 | G | CIITA, SOCS1 | 76.2/66.8 | 6.96 × 10−11 | 1.04/1.17 | 2.96%/10.20% |
| rs2286672 | T | PLD2 | 38.1/7.1 | 1.93 × 10−266 | 1.18/1.24 | 6.42%/1.68% |
| rs887369 | C | CXorf21 | 97.0/74.7 | 1.36 × 10−64 | 1.16/1.16 | 13.43%/10.68% |
(A) RAF: risk allele frequency; OR: odds ratio; PARP: population-attributable risk percentage; SNP: single nucleotide polymorphism.
(B) The significant associations were noted in bold.