Table 1.
General and metabolic characteristics of the healthy subjects, patients with coronary artery disease (CAD), and patients with type 2 diabetes (Diabetes)
| Healthy subjects | CAD | Diabetes | |
|---|---|---|---|
| Number | 1665 | 528 | 201 |
| Age, years | 41 ± 12 | 67 ± 11a | 61 ± 12a,b |
| Sex, M/F | 954/711 | 414/114 | 125/76 |
| Diabetes, n (%) | 0 | 174 (33) | 201 (100) |
| Total cholesterol, mg/dl | 195.5 ± 33.5 | 197.1 ± 36.4 | 205.3 ± 49.6a,b |
| HDL-C, mg/dl | 62.0 ± 15.3 | 47.2 ± 13.5a | 48.2 ± 13.3a |
| TG, mg/dl | 95.0 ± 65.2 | 131.5 ± 76.1a | 142.0 ± 85.1a |
| LDL-C, mg/dl | 113.9 ± 31.6 | 119.6 ± 32.4a | 129.2 ± 40.4a,b |
| sdLDL-C, mg/dl | 25.0 ± 13.0 | 35.3 ± 20.5a | 40.3 ± 24.9a,b |
| lbLDL-C, mg/dl | 88.9 ± 24.9 | 84.3 ± 29.1a | 88.9 ± 31.7 |
| Non-HDL-C, mg/dl | 133.4 ± 33.7 | 149.9 ± 35.5a | 157.1 ± 47.4a,b |
| sdLDL-C/LDL-C, % | 21.6 ± 8.3 | 29.6 ± 15.0a | 30.5 ± 14.5a |
| ApoB, mg/dl | 88.3 ± 23.4 | 98.0 ± 23.6a | 105.3 ± 31.4a,b |
| LDL-C/apoB | 1.29 ± 0.12 | 1.22 ± 0.17a | 1.23 ± 0.12a |
| LDL size, nm | 26.1 ± 0.51 | 25.6 ± 0.41a | 25.8 ± 0.50a,b |
Data are expressed as mean ± standard deviation
Significance at p < 0.0001–0.05 by ANOVA
CAD coronary artery disease, HDL-C high-density lipoprotein-cholesterol, TG triglyceride, LDL-C low-density lipoprotein-cholesterol, sdLDL-C small dense LDL-C, lbLDL-C large buoyant LDL-C, Non-HDL-C non high-density lipoprotein-cholesterol, Apo apolipoprotein
avs. Healthy subjects; bvs. CAD