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Number of variants by filter in three families using a dominant genetic model
| Filter system | Dominant model | |||
|---|---|---|---|---|
| Filter step | Filter process | Family A | Family B | Family C |
| Raw | – | 7523 | 3564 | 3227 |
| Filter 1 | EFFECT | 2799 | 2489 | 2198 |
| Filter 2 | IMPACT | 502 | 516 | 443 |
| Filter 3 | SIFT, PolyPhen2 | 278 | 258 | 231 |
| Filter 4 | phyloP | 234 | 225 | 206 |
| Filter 5 | Phastcon | 200 | 173 | 156 |
| Filter 6 | 1000 genome | 33 | 60 | 53 |
| Filter 7 | Korean | 31 | 54 | 49 |
