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l-Ornithine activation of human, mouse, and chimeric GPRC6A
The table is based on results from three independent IP1 accumulation assays performed as in Fig. 1B. NA, no activity in the assay; CI, confidence interval.
| pEC50 ± S.E. | EC50 | 95% CI | |
|---|---|---|---|
| μm | μm | ||
| h6A | NA | ||
| m6A | 4.40 ± 0.07 | 40.2 | 29.2–55.5 |
| h6A/m6A_ICL3 to C-tail | 4.82 ± 0.08 | 15.0 | 10.5–21.4 |
| H6A/m6A_ICL3 | 4.64 ± 0.08 | 23.0 | 16.2–32.7 |
| h6A/m6A_C-tail | NA | ||
| h6A/m6A_ICL3 + C-tail | 4.81 ± 0.09 | 15.5 | 10.4–23.2 |
