Figure 1.

Filtering strategy for RNASeq candidate events generated by MISO. Initial lists of candidate differential splicing events were produced by MISO using stringent criteria (see Methods). These lists were filtered to retain only those events which occurred in more than half of the pairwise comparisons between FECD samples and controls, yielding a combined total of 101 events from the two data sets. Twenty-four validated events present in both data sets are detailed in Table 2. The full set of 101 events is provided in Supplementary Table S2.