. 2016 Dec 8;8(12):3321–3340. doi: 10.18632/aging.101121

Table 4. Differentially expressed genes between p65^high vs. p65⁻ patients with diffuse large B-cell lymphoma (DLBCL) in the overall cohort and in the germinal-center-B-cell-like subgroup.

Functional categories	p65^high vs. p65⁻ DLBCL (FDR <0.15)	p65^high GCB vs. p65⁻ GCB (FDR <0.05)
Signaling, ion channels	*IL10RA ↑ GPS2 /// D4S234E ↑ NOTCH3 ↑ VAV1 ↑*	*FAM26F ↑ MT1X ↑ MT1G ↑ MT2A ↑ MT1F ↑ CFLAR ↑ CLEC7A ↑*
Immune responses, inflammation	*GRN ↑*	*CD163 ↑ GRN ↑ FCER1G ↑ CD84 ↑ CYBB ↑*
Cell cycle, DNA metabolism, transcription and translation regulation	*JUN ↑ PRDM1 ↑ GATAD2A ↑ TCF25 ↑ MLLT10 ↑ EP400 ↑ HOXD10 ↑* TAF1B ↓ ZNF254 ↓ RPL37A ↓ UHRF1 ↓ MCM10 ↓ BTG3 ↓	*JUN ↑ GATAD2A ↑ RBMS1 ↑*
Apoptosis	*TMBIM6 ↑ RNF130 ↑* BIRC6 ↓	*RNF130 ↑*
Metabolism, redox regulation	*SLC9A9 ↑ ATP6V0C ↑ SLC25A16 ↑ SAT1 ↑ SMPD1 ↑ C10orf58 ↑ HNMT ↑ GTPBP2 ↑*	*CPD ↑ GLUL ↑ SAT1 ↑ FTL ↑ ANKRD11 ↑ SLC9A9 ↑*
Transport, trafficking, protein folding, modification	*NPC2 ↑ WASH3P ↑ FTL ↑ GM2A ↑ KDELR1 ↑ SLC39A7 ↑ CTSD ↑ CALU ↑*	*SLC8A1 ↑ GM2A ↑ DNAJC5 ↑ BCAP31 ↑ NPC2 ↑*
Cell adhesion, cytoskeleton, collagen, extracellular matrix	*ITGB2 ↑ MYLK ↑ CD84 ↑ FMOD ↑*	*IQGAP1 ↑ UTRN ↑*
Degradation	*CTSZ ↑ IDS ↑*	*IDS ↑*
IncRNA genes, other function	*PLEKHO2 ↑LOC100288142 /// NBPF1 /// NBPF10 ↑ CCHCR1 ↑ IGLJ3 ↑* DLEU2 /// DLEU2L ↓ NOL10 ↓	*MT1P2 ↑ PLEKHO2 ↑ ZDHHC20 ↑*

Abbreviations: p65^high, high p65 nuclear expression (immunohistochemistry results: ≥50%); p65⁻, negative p65 nuclear expression (immunohistochemistry results: <10%); FDR, false discovery rate. *Upregulated genes in bold.

Table 4. Differentially expressed genes between p65high vs. p65− patients with diffuse large B-cell lymphoma (DLBCL) in the overall cohort and in the germinal-center-B-cell-like subgroup.

Table 4. Differentially expressed genes between p65^high vs. p65⁻ patients with diffuse large B-cell lymphoma (DLBCL) in the overall cohort and in the germinal-center-B-cell-like subgroup.