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. 2016 Dec 6;8(12):3390–3399. doi: 10.18632/aging.101128

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Copyright: © 2016 Marongiu et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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Panels (A) and (B) Histochemical staining for DPPIV of liver samples obtained from rats transplanted with pre-neoplastic hepatocytes at young age and killed 8 months after Tx. Small clusters of DPPIV-expressing hepatocytes (orange-rust) were discerned in all animals. Histochemical staining for DPPIV (panel C) and standard H&E staining (panel D) of a large hepatic nodule from a rat transplanted with pre-neoplastic hepatocytes at old age and killed 8 months later. Note the typical appearance of nodular hepatocytes arranged in multiple cell-thick plates. Magnification: 100x.