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. 2017 Jan 27;8:44. doi: 10.3389/fimmu.2017.00044

Figure 3.

Figure 3

Expression of interleukin (IL)-12, IL-23, and IL-17 mRNA in tumor and inflamed tissue of p47phox−/− and wild-type (WT) mice. (A) Expression of IL-23p19, (B) IL-17, (C) IL-12p35, and (D) IL-12/23p40 mRNA in tumor and inflamed tissue from p47phox−/− and WT mice treated with or w/o CpG was determined by quantitative real-time PCR. Results are mean ± SEM and representative of three independent experiments with n = 12–22 samples. General differences between p47phox−/− and WT mice were tested for statistical significance (*P < 0.05; **P < 0.01). Differences between tumor and inflamed tissue from p47phox−/− and WT mice, respectively, were tested for statistical significance (#P < 0.05; ##P < 0.01; and ###P < 0.001).