Table 1. Overlap of proteomic aging signature between study samples and previous report.

Cohort	Size of Aging Signature*	Overlap Genes**	Overlap odds ratio	Overlap pvalue
UC	221	CCDC80, CHRDL1, CST3, FSTL3, ROR1, THBS4	6.29	0.0055
CD	108	CCDC80, FSTL3, IGFBP6, THBS4	6.48	0.0106
NC	43	CHRDL1	2.84	0.3231

* Number of proteomic traits with nominal pvalue≤0.05 of positive association with aging.

**Genes overlapping with aging signature reported by Menni et al [4]; all 10 genes in Menni et al [4] were reported as having a positive association with aging.