Table 2. Summary of results yielded under fixed-effect and random-effects models.
Outcomes | No. of trials | Fixed-effect model | Random-effects model | Heterogeneity | |||||
---|---|---|---|---|---|---|---|---|---|
Effect size | 95% CI | P value | Effect size | 95% CI | P value | P value | I2 | ||
DGF | 6 | 0.84 | 0.60–1.18 | 0.32 | 0.89 | 0.61–1.28 | 0.52 | 0.40 | 3% |
AR | 4 | 0.95 | 0.62–1.46 | 0.81 | 0.96 | 0.62–1.49 | 0.86 | 0.51 | 0% |
Graft loss | 4 | 0.89 | 0.35–2.27 | 0.81 | 0.90 | 0.32–2.52 | 0.84 | 0.40 | 0% |
50% fall in SCr | 3 | 1.05 | 0.84–1.30 | 0.68 | 1.05 | 0.70–1.57 | 0.81 | 0.03 | 70% |
eGFR 3m | 4 | 1.23 | -1.73–4.19 | 0.41 | 1.23 | -1.73–4.19 | 0.41 | 0.61 | 0% |
eGFR 12m | 2 | 3.35 | -1.49–8.19 | 0.18 | 3.01 | -3.26–9.29 | 0.35 | 0.21 | 37% |
Hospital stay | 4 | -0.73 | -1.56–0.11 | 0.09 | -0.73 | -1.56–0.11 | 0.09 | 0.46 | 0% |
DGF: delayed graft function; AR: acute rejection; SCr: serum creatinine; eGFR: estimated glomerular filtration rate; CI: confidence interval.