Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 21;3:23. doi: 10.1186/s40580-016-0083-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 2 — General design scheme of NanoScript. a NanoScript is consist of a single 10 nm gold nanoparticle, DNA binding domain (DBD), activation domain (AD), and nuclear localization signal (NLS). The assembly of all components mimics a natural transcription factor. b Comparison of NanoScript with a natural transcription factor. c The DBD and AD domains on NanoScript work synergistically to mimic natural transcription factors for transcriptional modulation on expression of targeted genes. d1 and d2 NanoScript shows high mono-dispersity, efficient uptake, and nuclear localization [18]