Table 5. Evaluation of the Beta-Cell Function and Insulin Sensitivity/Resistance of the Rats.
S/N | Group | HOMA-IR | HOMA-B | Insulin Sensitivity |
---|---|---|---|---|
1 | NDF | 2.83 ± 0.33 a,b | 53.98 ± 8.38 e | 1.33 ± 0.09 b,c |
2 | NDF25 | 2.22 ± 0.26 a | 38.23 ± 5.01 d | 1.44 ± 0.07 b,c |
3 | NDF35 | 2.18 ± 0.27 a | 27.31 ± 5.18 c | 1.43 ± 0.10 b,c |
4 | NDF45 | 2.86 ± 0.65 a,b | 8.85 ± 2.22 b | 1.27 ± 0.15 b,c |
5 | NDF55 | 3.59 ± 1.14 b,c | 0.64 ± 1.36 a | 1.40 ± 0.45 b,c |
6 | FDF | 4.15 ± 0.39 c | 53.29 ± 6.77 e | 1.09 ± 0.04 a,b |
7 | FDF25 | 3.99 ± 0.35 c | 40.58 ± 3.79 d | 1.08 ± 0.05 a,b |
8 | FDF35 | 8.85 ± 1.36 d | 29.94 ± 1.22 c | 0.77 ± 0.04 a |
9 | FDF45 | 4.66 ± 1.01c | 1.48 ± 1.37 a | 1.11 ± 0.16 a,b |
10 | FDF55 | 4.16 ± 1.53 c | 1.17 ± 0.78 a | 1.67 ± 0.92 c |
Data are presented as mean ± SD of 6–8 animals per group. Values with different superscript down the column indicate significant difference (p<0.05). NDF: Group fed with Normal Diet Feed + water and treated with normal saline as control; NDF25: Group fed with Normal Diet Feed + Water and treated with 25mg/kg bw, STZ.; NDF35: Group fed with Normal Diet Feed + Water and treated with 35mg/kg bw, STZ.; NDF45: Group fed with Normal Diet Feed + Water and treated with 45mg/kg bw, STZ; NDF55: Group fed with Normal Diet Feed + Water and treated with 55mg/kg bw, STZ.; FDF: Group fed with Fortified Diet Feed + 20% fructose and treated with Normal saline; FDF25: Group fed with Fortified Diet Feed + 20% fructose and treated with 25mg/kg bw STZ; FDF35: Group fed with Fortified Diet Feed + 20% fructose and treated with 35mg/kg bw STZ; FDF45: Group fed with Fortified Diet Feed + 20% fructose and treated with 45mg/kg bw STZ; FDF55: Group fed with Fortified Diet Feed + 20% fructose and treated with 55mg/kg bw STZ.