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Effect of VPA on SMN mRNA levels in the VALIANT Trial
| Group 1 (VPA/Placebo) | Group 2 (Placebo/VPA) | Treatment effect | |||
| V4 | V6 | V4 | V6 | p value | |
| FL-SMN mRNA (mol/ng) | 405.2 (218.3) | 433.9 (195.5) | 343.3 (103.9) | 424.2 (256.2) | 0.790 |
| N | 13 | 13 | 16 | 16 | |
| SMNΔ7 mRNA (mol/ng) | 186.3 (112.1) | 194.5 (86.6) | 153.8 (72.0) | 154.9 (100.1) | 0.268 |
| N | 13 | 13 | 18 | 18 | |
