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. 2017 Jan 25;37(1):BSR20160514. doi: 10.1042/BSR20160514

Figure 7. Effect of mTORC2 inhibition in the extended human model.

Figure 7

The PKB-S473P response is dependent on mTORC2 activity as seen when mTORC2 is inhibited in the model (dashed lines). The PKB-S473P response is totally abolished when mTORC2 is inhibited, both in the diabetic (red) and normal (blue) state.