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Lean, healthy male adults randomly received either PO or VCL on 2 occasions. Hepatic metabolism was measured using in vivo 13C, 31P, 1H and ex vivo 2H MRS combined with 2H2O and acetaminophen ingestion before and during hyperinsulinemic-euglycemic clamps with D-[6,6-2H2]glucose–labeled 20% glucose infusion.
