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Percentage efficacies of 1, 3, and 5 in different modules of the PD2 screening panel.
| Compound | % Efficacy at 10 μM dose
|
||||
|---|---|---|---|---|---|
| Insulin secretion | ApoE secretion | Wnt pathway | G2M cell cycle | Angiogenesis | |
| 1 | 6 % | −3 % | 2 % | 95 % | 130 % |
| 3 | 8 % | −1 % | 3 % | 11 % | 75 % |
| 5 | 6 % | 9 % | 3 % | 1 % | −6 % |
