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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Can J Diabetes. 2016 Sep 7;41(1):108–113. doi: 10.1016/j.jcjd.2016.07.002

Figure 8.

Figure 8

Internalization of the activated insulin-IRK complex. Signalling from within ENS of the activated IRK is depicted. The role of IRK-associated PTP and endosomal insulin degradation in terminating intracellular insulin signalling is shown.