Table 4.
Inter-line comparison of plaque burdens, based on duration of plaque deposition (p values)
| 4±1 M | Kruskal-Wallis: cortex 0.0001; hippocampus 0.0001 | |||
| 5XFAD | APPSwePS1ΔE9 | rTg9191 | Tg2576 | |
| 5XFAD | -- | (>0.9999) | 0.0132 | 0.0132 |
| APPSwePS1ΔE9 | (>0.9999) | -- | 0.0024 | 0.0024 |
| rTg9191 | 0.0132 | (0.216) | -- | (0.3504) |
| Tg2576 | 0.0456 | 0.0168 | 0.0024 | -- |
| 12±1 M | Kruskal-Wallis: cortex <0.0001; hippocampusa | |||
| 5XFAD | APPSwePS1ΔE9 | rTg9191 | Tg2576 | |
| 5XFAD | -- | 0.0003 | n.d. | 0.0003 |
| APPSwePS1ΔE9 | (0.0856) | -- | n.d. | 0.0024 |
| rTg9191 | n.d. | n.d. | -- | n.d. |
| Tg2576 | n.d. | n.d. | n.d. | -- |
Non-parametric analysis of variance (Kruskal-Wallis test), followed by Mann-Whitney test, corrected for multiple comparisons.
a
Mann-Whitney test only. Open boxes, cortex; shaded boxes, hippocampus.
() not significant with α = 0.05; n.d., data not available.