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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Ann Epidemiol. 2016 Nov 25;27(1):10–19. doi: 10.1016/j.annepidem.2016.11.008

Table 1.

Multilevel Model Variables: Description, Rationale, and Sample Statistics

Variable (units of
measure)
Rationale for Inclusion
Outcome whether
cancer patient was
diagnosed at a late
stage (regional or
distant =1, else=0)
Late stage diagnosis is indicative of lack of knowledge regarding
personal cancer risk, or the importance or availability of screening;
lack of timely or proximate access to services, lack of funds to pay
for, and cultural or other barriers related to utilization of timely
cancer screening.
Proport
ion*
Sdev
0.543 0.498
Person-level predictors (categorical variables coded into binary variables)
female Both male and female are included in the CRC study, with male
designated as the reference group.
0.487 0.500
African American The national statistics cite African Americans as a disadvantaged
group, with higher likelihood of late-stage CRC than whites, the
reference group.
0.112 0.315
Hispanic The national statistics cite Hispanics as a disadvantaged group,
with higher likelihood of late-stage CRC than whites, the reference
group.
0.080 0.271
Asian The national statistics cite Asians as a disadvantaged group, with
higher likelihood of late-stage CRC than whites, the reference
group.
0.031 0.172
White (ref) The reference group 0.765 0.424
Race all others This group includes American Indians, Pacific Islanders, and
others not defined above. We grouped them into a single indicator
for the regressions.
0.013 0.113
age < 50 CRC screening protocols recommend to start screening at age <50
for higher risk individuals
0.111 0.275
age 50–64 CRC screening protocols recommend to start screening at age 50
for average risk individuals; this is the prime age bracket for
screening
0.314 0.464
age 65–74 Medicare insurance coverage begins at age 65 for people who are
eligible for Social Security benefits
0.250 0.433
age 75+ (ref) Screening is not needed or recommended as often for older
individuals who have had regular screening at younger ages
0.325 0.468
County-level predictors (n = 2,471 counties in 40 states) mean sdev min max
Isolation white This index reflects the degree to which whites are proximate
to other whites in their county of residence
0.825 0.17 0.02 1.00
Isolation African
American
This index reflects the degree to which African Americans
are proximate to other African Americans in the county
0.141 0.19 0.00 0.88
Isolation Hispanic This index reflects the degree to which Hispanics are proximate to
other Hispanics in the county
0.094 0.151 0.00 0.98
Isolation Asian This index reflects the degree to which Asians are proximate to
other Asians in the county
0.016 0.031 0.00 0.43
Isolation Native
American
This index reflects the degree to which Native Americans are
proximate to other Native Americans in the county (statistics
exclude AK, not included in regressions)
0.034 0.112 0.00 0.94
Isolation Pacific
Islander
This index reflects the degree to which Pacific Islanders are
proximate to other Pacific Islanders in the county (statistics
exclude HI, not included in regressions)
0.002 0.004 0.00 0.58
Person-centered
isolation construct
This variable is constructed by retaining, for each individual, the
specific isolation index (above) that reflects their race or ethnicity.
This construct reflects the degree to which people are proximate to
others of their same race or ethnicity in their county of residence.
0.719 0.227 0.00 0.94
Managed care
penetration (%)
Managed care has transformed the way medicine is practiced in
highly-penetrated markets, with preventive care services more
prevalent/utilized more intensively (2005).
4.83 8.83 0.00 53.49
Distance (miles) Calculated as the average distance (miles) over all ZIP codes with
centroid in the county to closest provider ZIP code. Greater
distance to provider of CRC (endoscopy) screening suggests
impeded access to preventive care services. Based on 100% FFS
Medicare utilization of CRC screening endoscopy services (2006).
12.10 9.74 0.00 72.45
Screening rate (%) Percent of the 100% FFS Medicare population residing in the
county and alive all year that utilized CRC screening by
endoscopy in 2006.
10.32 1.78 1.15 18.18
Percent uninsured % of the under-age-65 population with no health insurance (2005) 18.92 6.21 7.10 46.80
Percent Rural % of county population living in rural area (2005) 59.88 30.59 0.00 100
Percent Poverty % of county population living in poverty (2005) 15.96 6.71 2.50 51.00

(* mean of binary variable)