Table 5.

Prior case series and reports of eye disease in Ebola virus disease survivors

Author	Site / Organization	Key Findings
Kibadi et al5	Kikwit General Hospital, DRC	Four survivors of 1995 Ebola outbreak of DRC developed ocular symptoms of ocular pain, lacrimation and decreased visual acuity. Anterior and posterior uveitis documented 42–72 days following acute diagnosis, all of which improved with steroids and 1% atropine
Mattia et al8	Lunsar Baptist Eye Hospital, Port Loko, Sierra Leone	Uveitis was observed in 50 of 277 survivors (18%)Higher Ebola virus load associated with uveitis and new ocular symptoms or diagnosis
Tiffany et al11	MSF, Kissy UMC Hospital, Freetown, Sierra Leone	Ocular disease observed in 94/ 166 survivors; Uveitis was documented in 57 (34%) patients. Survivors were 10- times more likely to develop uveitis if they presented with red/injected eyes during acute phase
Scott et al9	Military Hospital 34, Freetown, Sierra Leone	Six of 44 survivors with ophthalmic problems; Symptoms included eye pain, discharge, red eyes, and blurred vision within two weeks after discharge
Varkey et al7	Emory University (Sierra Leone)	Case report of HCW who developed anterior uveitis progressing to severe panuveitis. Live Ebola virus identified in aqueous humor 100 days after acute EVD
Chancellor et al6	University of Massachusetts (Liberia)	Case report of a HCW with anterior and intermediate uveitis with cystoid macular edema that responded to topical corticosteroids (anterior uveitis) and systemic prednisone (intermediate uveitis), also with elevated serum markers of inflammation
Chertow et al15	National Institutes of Health (Sierra Leone)	Case report of a 34-year-old HCW evacuated from Sierra Leone with critical illness requiring intubation; bilateral anterior and posterior uveitis observed at 33 days post EVD diagnosis

MSF Medecins sans frontieres

UMC United Methodist Church

DRC Democratic Republic of the Congo

EVD Ebola virus disease

HCW Health care worker