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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Trends Biochem Sci. 2016 Nov 1;42(2):111–129. doi: 10.1016/j.tibs.2016.09.010

Figure 4. smURFP: a far-red, biliverdin-binding fluorescent protein derived from the allophycocyanin α-subunit from the cyanobacteria Trichodesmium erythraeum.

Figure 4

(A) Purified smURFP (left) shows color reminiscent of the cartoon character’s (Smurf) skin. (B) SmURFP expressed in primary rat neurons. (C) Far-red/near-infrared FUCCI expressed in HEK293A cells. Red-tinted fluorescence corresponds to smURFP, which illuminates the G0/G1 phases, while green-tinted fluorescence corresponds to IFP2.0, which illuminates the S/G2/M phases. (D) HT1080 tumor xenografts stably expressing smURFP. Fluorescence is visible without injection of exogenous BV.