Lower D2R binding in dorsal striatum was associated with greater self-reported anhedonia as measured by the Scales for Physical and Social Anhedonia (SPSA) across diagnostic groups. HC, healthy control; SIB, sibling of individual with schizophrenia; SCZ, individual diagnosed with schizophrenia or schizoaffective disorder; D2R, dopamine D2 receptor; BPND, non-displaceable binding potential